Sessions rotate between seminar, journal club, and research-in-progress. Twice per month, students attend the HGG seminar speaker series. Once per month, students present their own work in short research-in-progress talks. Once per month, students participate in a journal club, featuring student-led discussions of published papers. Components: SEM. Grading: SUS.
Ecosystem Science and Policy (ECS)
Annales géopolitique (HGGMC) BCE et Ecricome - Major-Prépa
Introduction to the Earth's Ecosystem. Earth's ecosystems and the interactions of humans with them. Concepts in ecology, environmental science and policy. Components: LEC. Grading: GRD. Field Problems in Ecosystem Science and Policy.
Les ouvrages les plus utiles à citer en dissertation de HGG #4 Amérique
The blood-tumor barrier BTB hinders delivery of chemotherapeutic drugs to tumors in the brain; previous studies have shown that the BTB can be selectively opened by endothelial monocyte activating polypeptide-II EMAP-II , but the specific mechanism involved remains elusive. In this study, we found that microRNA miR expression in glioma vascular endothelial cells GECs was far lower than in human brain microvascular endothelial cells ECs. Overexpression of miR in GECs significantly decreased the expression of tight junction TJ -associated proteins ZO-1, occludin and claudin-5 , and decreased the distribution continuity. The dual-luciferase reporter assay revealed that ZO-1 and occludin were target genes of miR, and we demonstrated that miR overexpression markedly down-regulated protein expression of p70S6K, as well as its phosphorylation levels. The dual-luciferase reporter assay also showed that p70S6K was a target gene of miR; miR overexpression down-regulated expression and phosphorylation levels of p70S6K, and also decreased phosphorylation levels of S6 and increased BTB permeability.
Dissertation, au choix :. Au choix. Le Japon et la Chine, deux puissances concurrentes en Asie.